Corsi Block-tapping Task (CBT) Performance Experiment

Corsi Block-tapping Task (CBT) Performance Experiment Abstract The Corsi block-tapping task (CBT) is a widely used experimental tool for assessing visuo-spatial memory in both clinical and research contexts. However, whether information other than those spatial and visual (i.e., motor information) play also a role in CBT performance is still a matter of debate. Here, we investigated such issue through a crossed double dissociation design by observing how motor, visual, and spatial secondary tasks affect the performance on three versions of the CBT (standard, automatic and two-dimension). Results showed a double dissociation pattern, wherein two motor secondary tasks had larger effects when the CBT was administered by the examiner tapping on the blocks (standard version). A spatial secondary task had larger effects when the CBT was administered by automatically illuminating the blocks (automatic version). Finally, a visual secondary task had larger effects on a two-dimension, computerized version of the CBT. These findings suggest that memory for movements plays a relevant role in the CBT, and are especially relevant due to their implications for assessment of brain-damaged patients, besides providing further evidence of a fractionation of visuo-spatial memory into multiple sub-components. Keywords: Corsi block-tapping task, visuo-spatial memory, memory for movements. Acknowledgements: The study was supported by a MIUR grant C26F014219 to F.F. Introduction The Corsi Block Tapping test (Milner, 1971; Corsi, 1972) has been widely used in cognitive psychology and in clinical neuropsychology to measure visuo-spatial memory (e.g., Kessels, de Haan, Kappelle, Postma, 2003; Vandierendonck, Kemps, Fastame, Szmalec, 2004) usually within the framework provided by the working memory model (Baddeley Hitch, 1974). The standard apparatus consists of identical blocks irregularly arranged on a board. According to the standard administration procedure, but procedures vary widely among authors, the examiner taps on the blocks in randomized sequences of increasing length. The subject has to immediately reproduce each sequence, continuing until no longer accurate. Performance is measured as the longest sequence of blocks that is correctly reproduced. Notwithstanding Baddeley (2001) reported the CBT as the task that is most closely related to the visuo-spatial short term memory, it is still not clear what of the two components, visual or spatial, it actually measures (Berch, Krikorian, Huha, 1998; Quinn, 2008). This issue is relevant, since studies of both healthy individuals and brain-damaged patients demonstrated dissociable visual and spatial memory systems in humans (Klauer Zhao, 2004; Carlesimo, Perri, Turriziani, Tomaiuolo, Caltagirone, 2001). Such a fractionation of the visuo-spatial working memory is in fair agreement with evidence in primates of separate processing streams for visual and spatial features of objects (e.g., Goodale Milner, 1992). Indeed, it has been proposed in both primates and humans that the dorsal visual system supports spatial working memory functions, and that the ventral visual system supports visual working memory for features of objects (e.g., Goldman-Rakic, 1987). Evidences for a further fractionation of the visuo-spatial working memory were also reported, suggesting specific components of working memory for motor and kinesthetic information (Smyth, 1990). A close link between motor systems and visuo-spatial working memory was actually proposed since the very first studies about working memory (Baddeley, Grant, Wight, Thomson, 1975). However, Smyth and her co-workers (Smyth Pendleton, 1989) firstly suggested that a specific kinesthetic component of working memory might be responsible for the encoding and maintenance of remembered patterned movements (those aimed to bring the body parts into a specific configuration), whereas positional movements (movements targeted towards specific external spatial stimuli) appear to be encoded and maintained within the visuo-spatial sketchpad. Notwithstanding the evidence favorable to a fractionation of the visuo-spatial working memory into multiple components, not necessarily independent one of each other, their relationship with the CBT has been actually scarcely investigated in literature. Though, the complex administration procedure of the CBT makes a more detailed analysis of the processes underlying the CBT strongly needed (Berch, Krikorian, Huha, 1998). More interestingly, and maybe less obviously, the CBT might involve a memory for positional movements, because the administration procedure focuses on the movements of the examiner. However, the contribution of a memory for positional movements in the CBT task has never been investigated so far. It is also worth noting that computerized, two-dimension CBT versions have been frequently used (e.g., Vandierendonck, Kemps, Fastame, Szmalec, 2004), albeit it is not known whether the standard and the computerized versions of the task are equivalent. The present study aims at investigating the architecture of the visuo-spatial working memory as measured by the CBT, through a crossed double dissociation design (Dunn Kirsner, 1988). We followed a standard dual-task procedure, using four secondary tasks aimed at interfering with the spatial, visual, and motor components of visuo-spatial working memory. They were crossed with three versions of the CBT: a) a standard version, wherein the sequences were given by the experimenter tapping on the blocks; in this version of the CBT the supposed motor/positional component was fully present; b) an â€Å"automatic† version, wherein the sequences were given by the blocks being illuminated; in this version the motor/positional component was removed from the task, while the spatial component was unaffected; c) a two-dimension version, presented on a computer monitor, wherein the sequences were given by the squares on the monitor changing their color; in this version, the spatial componen t of the task was reduced, albeit obviously not eliminated, by requiring the task to be performed on a 2D plane instead than in a 3D space. Method Participants. Forty-eight healthy, right handed individuals (mean age 22.4 years) participated in the experiment. All the participants reported normal or corrected-to-normal vision, and were naà ¯ve as to the purposes of the experiment. Stimuli and apparatus. The apparatus was composed of eight translucent white 3 x 3 x 3 cm blocks, each one containing a red light emitting diode (LED). The blocks were fixed at random positions on a 23 x 30 cm translucent white board. Procedure. Three administration procedures were used. In the standard procedure participants observed the experimenter tapping on the blocks, with his/her index finger, at a rate of one block per s, lifting the hand straight up before moving it to the next block (Standard). In the second procedure the to-be-remembered sequence was presented by the computer turning on and off the red LEDs inside the blocks, at a rate of one block per s (Automatic). A third, two-dimension version of the CBT was also used, as it is frequently used in literature as a substitute of the standard version. It was composed of eight blue squares appearing on the computer screen at the same relative positions as the 3D version described above. On each trial, the to-be-remembered sequence was indicated by the blocks changing color from blue to red and again to blue, at a rate of one block per s. The CBT was administered to all the participants according to the three procedures described above, in random order. P articipants had to reproduce the sequence immediately after its administration, by tapping on the blocks using their index finger. Sequences from 3 to 9 blocks in length were presented in ascending order, with two trials per length. All the fourteen sequences were administered to each participant. For each subject, different sequences, equated for paths’ length, were randomly assigned to the three versions of the test. Each participant performed each version of the task both alone (single task condition), and along with one of four interference conditions (dual task condition), in random order: patterned-motor interference, motor interference, spatial interference and visual interference. In the patterned-motor interference condition, participants had to tap with their right index finger on the four corners of a mouse-pad, while the to-be-remembered sequence of blocks was administered. The movement had to be performed clockwise and continuously, at a rate of about one tap per s. Whereas this task is known to interfere with the CBT (Smyth Pelky, 1992), it has both spatial and motor features that makes it difficult to disentangle their contribution. Thus, to remove the spatial component from this task we added a motor interference condition, wherein participants had to snap fingers with their right hand, while the to-be-remembered sequence of blocks was administered. The movement had to be performed continuously, in a regular manner (one snap per s, approximately). The experimenter controlled for the movement being correctly executed. In the spatial interference condition, participants were required to say aloud the side of each of a series of 1000 Hz tones randomly presented to their left or right ear through headphones, at 30 Db Spl with a constant inter-stimulus interval of 2 s. This listening task is supposed to interfere with the spatial component of the visuo-spatial sketchpad [18]. Finally, in the visual interference condition, one of three LEDs placed at the center of the board (one of three colored circles in the Two-Dimension Version) were turned on and off at a rate of one per s. On half the trials the regular sequence was violated, by turning on a differently colored led (on the 3D versions) or displaying a different colored circle (on the 2D version). At the end of each trial, participants were required to say whether a violation occurred on that trial. Twelve participants were randomly assigned to the Patterned-motor, Motor, Spatial, and Visual Interference conditions, respectively. The participants’ performance was measured as the longest sequence that was correctly reproduced at least once (memory span). Performance data were analyzed in a 3x2x4 ANOVA mixed design, with Version (standard, automatic, and two-dimension, within subjects), Condition (single task, dual task, within subjects), and Interference (patterned-motor, motor, spatial, and visual interference, between subjects) as factors. Results One participant in the Spatial Interference condition and two participants in the Visual Interference condition have been excluded from the following analyses because of the relatively large number of errors committed on the interference tasks. The remaining participants performed all the interference tasks at optimal levels, committing less than 3% of errors across visual and spatial interference tasks, and maintaining a regular mean rate of finger snapping and spatial tapping of about 1.2 per s. Figure 1 and Table 1 show the mean memory span length for each version of the CBT and for each interference condition. A preliminary sphericity test failed to show any significant violation of the assumptions underlying the Version and the Version by Condition interference effects (p>.05 in all cases). The analysis of performance data showed significant main effects of Condition (F1,41=139.93, MSE=.42, p2,82=4.24, MSE=.63, p6,82=3.61, MSE=.63, p6,82=4.33, MSE=.63, p.05 in all cases). This finding ensures that the administration procedure did not affect the difficulty of the task. However, the effects of the four kinds of interference upon the three versions of the CBT were very specific. Indeed, the patterned-motor and the motor interference tasks affected negatively the standard version of the test (p.5 in both cases). The spatial interference task affected negatively the participants’ performance at the automatic version of the test (p.05 in both cases). The visual interference task affected negatively the participant’s performance at the two-dimension version of the test (p.05 in both cases). Importantly, such finding cannot be ascribed to the three interfering tasks being not equivalent with respect to each other, because of the triple dissociation procedure we em ployed. Discussion Results of the present experiment suggest that a component of working memory that deals with motor information has the major role in the standard version of the CBT. Indeed, the effects of both the motor and patterned-motor interference tasks were notably larger than those of the spatial and visual interference tasks in the standard version of the CBT. The crossed double dissociation general pattern of results strongly supports this interpretation. Indeed, the spatial interference task was more effective than both the motor interference tasks in the â€Å"automatic† version of the CBT, whereas only the visual interference task was effective in the two-dimension version of the CBT. Such result does not depend on confounding due to the three versions of the CBT being not equated in terms of difficulty, because in the single task condition the performance of the participants was the same in the three versions of the test. Also, it does not depend on the spatial interference task involving a verbal coding of the spatial locations where the tones came from, as the phonological loop has been shown to be not involved in the CBT (e.g., Vandierendonck, Kemps, Fastame, Szmalec, 2004). The finding that the performance on the standard version of the CBT largely depends on individuals coding the movements of the examiner is in fair agreement with the hypothesis that a component of working memory that deals with motor information actually exists, and is independent of the component of working memory that deals with spatial information (e.g., Smyth Pendleton, 1990). It is also in fair agreement with the growing body of neurophysiological and psychological studies that suggest a close link between observing and performing an action (e.g., Rizzolatti, Fadiga, Gallese, Fogassi, 1996). Interestingly, van Asselen and coworkers (van Asselen, Kessels, Sebastiaan, Neggers, Kappelle, Frijns, et al. 2006) have recently interpreted results of a study on stroke patients as suggesting that the right dorsolateral prefrontal cortex (DLPFC) and the right posterior parietal cortex (PPC) are involved in keeping spatial information in memory over a short time period, as was assessed wi th the CBT. While the involvement of both the DLPFC and the PPC in spatial memory tasks is not new (e.g., Walter, Bretschneider, Groen, Zurowski, Wunderlich, Tomczak, et al. 2003), it is worth noting that this is not at variance with the hypothesis that a specific component of working memory for positional movements is involved in the CBT. For instance, lesion and physiological studies have shown that the DLPFC has a crucial role in visuospatial control of actions and visuomotor transformations (e.g., Curtis D’Esposito, 2004). Indeed, Hoshi (Hoshi, 2006) in a recent review suggested that the dorsal part of the DLPFC is involved in representing processed motor information, such as arm use or target location, and in integrating multiple classes of information for planning action. Similarly, the PPC is involved in visuomotor transformation, and is thought to serve as a sensorymotor interface for visually guided eye and limb movements (Buneo Andersen, 2006). Moreover, evidence has been recently provided that, within the fronto-parietal network of brain regions involved in learning spatial sequences, two partially segregated neural systems are involved in processing spatial sequences in reaching and navigational space (Nemmi, Boccia, Piccardi, Galati Guariglia, 2013), supporting the idea of a further fractionation of visuo-spatial memory into multiple sub-components. Though, more research is needed in order to specify the relationship between the complex functional architecture of the DLPFC – PPC system and the specific features of the working memory components, including those measured by the CBT. Finally, it is worth noting that the motor and spatial interference tasks affected only marginally the performance on the two-dimension version of the CBT. Such a result suggests that the two-dimension and the standard versions of the CBT cannot be considered as equivalent. This finding is especially relevant because recently two-dimensions, computerized versions of the CBT have been used rather frequently in clinical and experimental settings (Vandierendonck, Kemps, Fastame, Szmalec, 2004; Joyce, Robbins, 1991). In conclusion, the present study shows that the performance on the Corsi block-tapping task  depends largely on a component of working memory specifically dealing with motor information and that this component is independent of that component of working memory that deals with spatial information. Beside providing further evidence of a fractionation of visuo-spatial memory into multiple sub-components, present findings have important implications for clinical assessment of brain-damaged patients and should be taken into account when interpreting the performance on the CBT for neuropsychological rehabilitation treatments in clinical settings.

Writing and Classification Essay Sample

A classification essay is written by classifying the subject or matter into various divisions or categories. The purpose is it organizes ideas into appropriate and constructive categories. Some very good classification essay sample topics would be Music, books, movies, sports, etc. If classification essay sample is, for example, on topic sports then it would look like this 1. Introduction to sports- explain here briefly how you are going to categorize sports. 2. Classification of sports- write here the categories of sports in detail †¢Indoor games 1. Board games 2. Court games 3. Table games †¢Outdoor games . Athletics 2. Team games like football, cricket 3. Individual games like tennis, badminton †¢Summary of sports – end it with a summary on sports This is a short example of how a classification essay should look. †¢Ã¢â‚¬ Americans can be divided into three groups–smokers, nonsmokers and that expanding pack of us who have quit. Those who have neve r smoked don't know what they're missing, but former smokers, ex-smokers, reformed smokers can never forget. We are veterans of a personal war, linked by that watershed experience of ceasing to smoke and by the temptation to have just one more cigarette.For almost all of us ex-smokers, smoking continues to play an important role in our lives. And now that it is being restricted in restaurants around the country and will be banned in almost all indoor public places in New York State starting next month, it is vital that everyone understand the different emotional states cessation of smoking can cause. I have observed four of them; and in the interest of science I have classified them as those of the zealot, the evangelist, the elect and the serene. Each day, each category gains new recruits. â€Å"

Alzheimer s Disease Treatments And Stages Of The Disease

When I began, I knew next to nothing about this deadly disease. All I knew was that it was a widespread and dangerous disease, capable of ruining the lives of many American people. When I found the topic, I had been researching about different forms of degenerative diseases in the hopes of finding a suitable topic for my project. I saw Alzheimer’s was both the most common disease in the field and the most deadly, and immediately I decided. After finding the topic, I began researching the guiding question of my research: What treatments are currently available to treat Alzheimer’s and what entails the different stages of the disease? This question was the northern star of my research, and provided a great tool to stay focused on a specific†¦show more content†¦It was not always easy though, I had to dig through many advertisements to find what I was looking for. Many sites attempted to sell their services to me, or to provide information to me about the types of care they offered. However these were not the sites that I was looking for to learn more information, so I turned to government and international organizations for my information. Sources that I used frequently included Centers for Disease Control and Prevention, the World Health Organization, and the National Institute on Aging. These sources all were a great help to my research, providing accurate and ample information for my research. After learning the basics, I then turned to the more advanced information on Alzheimer’s disease specifically. I had to dig deeper past the basic information provided on the government sites, and turn to some sites that specifically offer information about Alzheimer’s disease. To do this, I began researching on sites that offered detailed data on the topic, namely the Alzheimer’s Association and Alzheimer’s Organization. As I went on, I learned that there were a very limited number of effective treatments, which I realized would provide more support on my topics validity. I also learned about the various differences between stages of Alzheimer’s progression, sparking more interest on my part for the topic. During the time I was researching I was also planning an interview with a doctor from my local area.

Brand Identity Prism of Raymonds and Arrow - 1126 Words

KOLKATA DEPARTMENT OF FASHION MANGEMENT STUDIES Subject: Fashion Brand Management Topic: Comparative study of the Brand Identity of two Fashion Brands Arrow Raymond Premium Apparel Submitted to: Mrs. Bharti Moitra Submitted By: Nancy Mehta Roll no.27 MFM (Sem-II) Brand Identity Brand identity is a unique set of brand associations that the brand strategist applies to create or maintain. These associations represent what the brand stands for and imply a promise to the customers from the organization members. Modern theories say that a brand identity provides not only the personality of the brand but also the direction, purpose and meaning for the brand. Brand identity is the aggregation of what all you (i.e. an†¦show more content†¦Arrow was popular among the older business class. The company felt that the brand is losing its position among the emerging young turks. In 2008 the company designed to reposition itself to target the youth. Today’s Arrow Collar Man is a modern symbol of masculine American style. Cluett Peabody is committed to providing worldwide quality ARROW brand apparel products that embody the heritage of the brand and deliver superior quality to consumers. One hundred and sixty years ago, the detachable collar was the innovation that changed an industry. Today, the ARROW brand represents another novel idea to modern men: choose value but never sacrifice style. The brand adopted a new tagline When You Know . Arrow had established itself in the market not because of its campaigns but because of the quality, premiumness and exclusivity. BRAND IDENTITY PRISM Raymond Premium Apparel Raymond, the name is synonymous with the values of trust, heritage excellence. A name that has over eight decades epitomized consumer s trust into its offerings into the company s unflinching faith in the quality of its product. And now these values have been extended to the range of readymade garments - Raymond Premium Apparel . Raymond Premium Apparel is a premium formal wear brand which is positioned to offer classic garments with impeccable fits and inviting styles to the Global Indian. The product is made only from premium Raymond fabrics. The brand